I just finished reading this along with your podcasts. Excellent job again. I haven't read ahead, I am reading this for the first time. A few thoughts.
The repeated experiments on each generation of clone isn't a abuse cycle like people in our world experience. It is beyond that and into the realm of torture as expermentation so the fathers explanation doesn't make sense unless they are trying to unlock genetic memories.
The nature/nurture left me with questions. It discounts the brother David as an influence unless all other previous clones also had a brother? Why would each clone come to the same conclusions as the previous ones? This would seem to preclude the idea of original thoughts or that our ability to chose is always predetermined by our genetics and formative years.
Mr. Millions is the true villain of this story. None of this clone business would work out without him guiding each generation. There would be no ability to have a clone be raised the same without his guidance. The original human who uploaded himself into Mr. Millions also created the first clone and was obsessed with retaining his memories for some reason? To cheat death?
I enjoyed your references to the Rhyme of the Ancient Mariner. In the poem the sin caused the ship to be stuck in becalmed zone with no wind. In Fith head the whole planet is becalmed as shown be the ships with 5 or 7 masts. A ship like that on earth would be torn apart by normal winds or storms so they must not exist on St. Croix.
On my first reading I thought John V. Marsch was also killed by the narrator but the text doesn't support that.
Looking forward to the next novella and your podcast.